Endocrine Abstracts

Introduction: Due to the absence of randomized controlled trials, management of low risk papillary thyroid cancer (PTC), which represents the most commonly diagnosed form of thyroid malignancy, remains controversial. Hashimoto’s thyroiditis (HT) is significantly more frequent in patients with PTC, as compared with subjects carrying benign lesions as well as different tumour histotypes. Despite still controversial, HT is considered a protective factor in PTC being associat...

Introduction: Constitution of new blood vessels is crucial for cancer self-maintenance and progression. Neo-angiogenesis may be affected from hereditary traits, namely the presence of SNPs (single nucleotide polymorphisms) of genes involved in its regulation. VEGF-A represents the main regulator of angiogenesis. Germline SNPs of the VEGF-A gene have been associated to outcome of several cancers, but no data exist about differentiated thyroid cancer (DTC).<p class="abstext"...